DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [GO_0003918]
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
ID: GO_0003918
Class
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.
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Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| type II DNA topoisomerase activity | related synonym | krc |
| DNA topoisomerase (ATP-hydrolysing) | related synonym | krc |
| DNA topoisomerase II | narrow synonym | krc |
| DNA topoisomerase II activity | narrow synonym | krc |
| topoisomerase II | narrow synonym | krc |
| DNA topoisomerase IV activity | narrow synonym | krc |
| deoxyribonucleic topoisomerase activity | broad synonym | krc |
| topoisomerase | broad synonym | krc |
| deoxyribonucleate topoisomerase | broad synonym | krc |
| DNA topoisomerase type II activity | exact synonym | krc |
References
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